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Yet, amazingly, by chance, this natural insecticide's chemical structure is so similar to the neurotransmitter acetylcholine that once inside the brain it fits a host of chemical locks permitting it direct and indirect command and control over the flow of more than 200 neurochemicals, including dopamine, serotonin and adrenaline

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Abrams, Promise and Peril of Ecigarettes: Can Disruptive Technology Make Cigarettes Obsolete?, JAMA 311, no

Interestingly enough, E-cigarettes were created to help current smokers try a better alternative to cigarettes in the name of quitting the habit